About Help FAQ

Symbol
Name
ID

Prop1
paired like homeodomain factor 1
MGI:109330

Phenotype annotations related to nervous system

Darker colors indicate more annotations

Human Phenotypes

Hypoglycemic seizures

Decreased response to growth hormone stimulation test

Ectopic posterior pituitary

Posterior pituitary hypoplasia

Anterior pituitary agenesis

Anterior pituitary hypoplasia

Ectopic anterior pituitary gland

Hypopituitarism

Anterior hypopituitarism

Abnormal prolactin level

Reduced circulating prolactin concentration

Gonadotropin deficiency

Panhypopituitarism

Pituitary hypothyroidism

Optic nerve hypoplasia

Septo-optic dysplasia

Agenesis of corpus callosum

Absent septum pellucidum

Holoprosencephaly

Intellectual disability

Severe global developmental delay

Seizure

Disease(s) Associated with PROP1

hypopituitarism

panhypopituitarism

Mouse Phenotypes		abnormal pituitary gland morphology	abnormal adenohypophysis development	absent somatotrophs	decreased thyrotroph cell number	small adenohypophysis	adenohypophysis hypoplasia	abnormal neurohypophysis morphology	abnormal pituitary gland development	pituitary gland hypoplasia	hypopituitarism
Availability	Mouse Genotype	abnormal pituitary gland morphology	abnormal adenohypophysis development	absent somatotrophs	decreased thyrotroph cell number	small adenohypophysis	adenohypophysis hypoplasia	abnormal neurohypophysis morphology	abnormal pituitary gland development	pituitary gland hypoplasia	hypopituitarism
	Prop1^df/Prop1^df
	Prop1^tm1Rsd/Prop1^tm1Rsd
	Prop1^tm1Sac/Prop1^tm1Sac
	Prop1^tm1Sac/Prop1⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/30/2024 MGI 6.23